De Kruif is known to have drawn inspiration for locations and characters in Arrowsmith from specific sources. The labwork and experimental process of Max Gottlieb was based on the careers of F. G. Novy and Jacques Loeb. Loeb and De Kruif both worked at the Rockefeller Institute for Medical Research in New York and Novy was de Kruif's longtime mentor.

Pulitzer Prize  Arrowsmith was awarded the 1926 Pulitzer Prize, but Lewis declined the award. In a letter to the committee, he wrote:  "I wish to acknowledge your choice of my novel Arrowsmith for the Pulitzer Prize. That prize I must refuse, and my refusal would be meaningless unless I explained the reasons.  All prizes, like all titles, are dangerous. The seekers for prizes tend to labor not for inherent excellence but for alien rewards; they tend to write this, or timorously to avoid writing that, in order to tickle the prejudices of a haphazard committee. And the Pulitzer Prize for Novels is peculiarly objectionable because the terms of it have been constantly and grievously misrepresented.  Those terms are that the prize shall be given "for the American novel published during the year which shall best present the wholesome atmosphere of American life, and the highest standard of American manners and manhood." This phrase, if it means anything whatsoever, would appear to mean that the appraisal of the novels shall be made not according to their actual literary merit but in obedience to whatever code of Good Form may chance to be popular at the moment."


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    Arrowsmith
    by
    Sinclair Lewis
    eBooks@Adelaide
    2010

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    This web edition published by eBooks@Adelaide .

    Rendered into HTML by Steve Thomas .

    Last updated Sat Aug 28 20:22:56 2010.

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    (available at http://creativecommons.org/licenses/by-nc-sa/2.5/au/ ). You are free: to copy, distribute, display, and perform the work, and to make derivative works under the following conditions: you must attribute the work in the manner specified by the licensor; you may not use this work for commercial purposes; if you alter, transform, or build upon this work, you may distribute the resulting work only under a license identical to this one. For any reuse or distribution, you must make clear to others the license terms of this work. Any of these conditions can be waived if you get permission from the licensor. Your fair use and other rights are in no way affected by the above.

    eBooks@Adelaide
    The University of Adelaide Library
    University of Adelaide
    South Australia 5005

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    TABLE OF CONTENTS

    Chapter 1

    Chapter 2

    Chapter 3

    Chapter 4

    Chapter 5

    Chapter 6

    Chapter 7

    Chapter 8

    Chapter 9

    Chapter 10

    Chapter 11

    Chapter 12

    Chapter 13

    Chapter 14

    Chapter 15

    Chapter 16

    Chapter 17

    Chapter 18

    Chapter 19

    Chapter 20

    Chapter 21

    Chapter 22

    Chapter 23

    Chapter 24

    Chapter 25

    Chapter 26

    Chapter 27

    Chapter 28

    Chapter 29

    Chapter 30

    Chapter 31

    Chapter 32

    Chapter 33

    Chapter 34

    Chapter 35

    Chapter 36

    Chapter 37

    Chapter 38

    Chapter 39

    Chapter 40

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    Last updated on Wed Jan 12 09:40:45 2011 for eBooks@Adelaide.

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    Arrowsmith, by Sinclair Lewis

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    CHAPTER 1

    The driver of the wagon swaying through forest and swamp of the Ohio wilderness was a ragged girl of fourteen. Her mother they had buried near the Monongahela — the girl herself had heaped with torn sods the grave beside the river of the beautiful name. Her father lay shrinking with fever on the floor of the wagon-box, and about him played her brothers and sisters, dirty brats, tattered brats, hilarious brats.

    She halted at the fork in the grassy road, and the sick man quavered, “Emmy, ye better turn down towards Cincinnati. If we could find your Uncle Ed, I guess he’d take us in.”

    “Nobody ain’t going to take us in,” she said. “We’re going on jus’ long as we can. Going West! They’s a whole lot of new things I aim to be seeing!”

    She cooked the supper, she put the children to bed, and sat by the fire, alone.

    That was the great-grandmother of Martin Arrowsmith.

    II

    Cross-legged in the examining-chair in Doc Vickerson’s office, a boy was reading “Gray’s Anatomy.” His name was Martin Arrowsmith, of Elk Mills, in the state of Winnemac.

    There was a suspicion in Elk Mills — now, in 1897, a dowdy red-brick village, smelling of apples — that this brown-leather adjustable seat which Doc Vickerson used for minor operations, for the infrequent pulling of teeth and for highly frequent naps, had begun life as a barber’s chair. There was also a belief that its proprietor must once have been called Doctor Vickerson, but for years he had been only The Doc, and he was scurfier and much less adjustable than the chair.

    Martin was the son of J. J. Arrowsmith, who conducted the New York Clothing Bazaar. By sheer brass and obstinacy he had, at fourteen, become the unofficial, also decidedly unpaid, assistant to the Doc, and while the Doc was on a country call he took charge — though what there was to take charge of, no one could ever make out. He was a slender boy, not very tall; his hair and restless eyes were black, his skin unusually white, and the contrast gave him an air of passionate variability. The squareness of his head and a reasonable breadth of shoulders saved him from any appearance of effeminacy or of that querulous timidity which artistic young gentlemen call Sensitiveness. When he lifted his head to listen, his right eyebrow, slightly higher than the left, rose and quivered in his characteristic expression of energy, of independence, and a hint that he could fight, a look of impertinent inquiry which had been known to annoy his teachers and the Sunday School superintendent.

    Martin was, like most inhabitants of Elk Mills before the Slavo–Italian immigration, a Typical Pure-bred Anglo–Saxon American, which means that he was a union of German, French, Scotch, Irish, perhaps a little Spanish, conceivably a little of the strains lumped together as “Jewish,” and a great deal of English, which is itself a combination of primitive Briton, Celt, Phoenician, Roman, German, Dane, and Swede.

    It is not certain that, in attaching himself to Doc Vickerson, Martin was entirely and edifyingly controlled by a desire to become a Great Healer.